LGD 3303 Review: Is This New Supplement the Best SARM for You?

What is LGD 3303?

We have been dazzled by all the great things SARMs can do but what can LGD 3033, the newest arrival to this class of compounds do for you as a bodybuilder or fitness person? Before I go on, let me quickly describe for you what SARMs are.

SARMs is your shorthand name for Selective Androgenic Receptor Modulators.  As the name suggests, these compounds do a lot of selecting which they perform on certain receptors in the body. If you haven’t heard about them, SARMs have quickly become the popular substitute in favor of anabolic steroids in the bodybuilding and athletic world.

But the SARMs world (being still in ongoing research) is also notorious for its poverty of information as well as its glut of myths. It doesn’t help that more and more new SARMs are coming out into the market, adding to the lack of information and myths.

As the new kid in the block, LGD 3033 also seems to have come surrounded with mystery leaving users digging for information, sometimes from less credible sources.

In fact, so new is LGD 3033 that even the World Anti-Doping Agency doesn’t know how to test for it in case you used it for a competition (meaning you could easily pass a doping test even if you are on LGD 3033)!

In this article, I will help you to see past the myths and mystery to answer the question: Is LGD 3033 good or any better than its well known SARMS peers? But let me first give a little history of LGD 3033.


Lingad Pharmaceutical Inc is the company that came up with LGD 3033. In their still ongoing research, they wanted to look into whether LGD 3033 could make a good oral supplement for treating weak bones (osteoporosis) and muscle wasting, which affects older people.

As recent as 2007, the company started their research with animal models. The findings gave impressive results showing that muscle mass and BMD (Bone Mineral Density) could be significantly increased or improved by the use of this substance.

The chemical structure of this sarms is much like LGD 4033, another SARM which was also created by Lingad Pharmaceuticals. However, LGD-4033, unlike  LGD 3033, has already been released into the market and is available for buyers.


Despite its newness, LGD-3033 happens to be a highly rated SARMS in terms of its sheer potency for building muscle mass and strengthening bones. Not only does ongoing research suggest this, but users have even compared it to some of the heavyweights in the anabolic steroids world such as Sustanon, Dianabol, Trenbolone, and Deca.

These anabolic steroids pack a lot of strength, so this says a lot about LGD-3033 to be compared with them.

If you want to go the way of LGD-3033, some or any of these benefits could land straight into your laps.

  • Increased libido in women.

Some studies show that LGD-3033 can be used to treat some sexual disorders in women.

  • Has low water retention

This gives you huge dry mass gains and great muscle definition

  • Great muscle fullness: this is a surprising result of LGD 3033. This result is more typical of wet compounds (those that have water retention), but LGD 3033 gives dry mass. Its exceptional nitrogen retention could be the cause of this.
  • Can be used for longer cycles
  • Your body’s testosterone production will not be affected
  • No prostate gland enlargement or shrinkage
  • Has a high absorptive capacity

Studies show that LGD 3033 has one of the highest rates of bioavailability giving your body maximum benefits

  • Has accelerating effect on metabolism

LGD 3033 quickens up metabolism rates in the body which makes it ideal for burning fat

  • Cutting, bulking and recomping
  • Other SARMs typically seem more suited for only one of these more than the others, but LGD 3033 seems ideal in providing all three benefits in a rare combination.
  • This makes LGD 3033 very versatile among the SARMS. LGD-3033 is also adept at making you preserve lean muscle even in a caloric deficit. Another attraction of LGD-3033 is that you will see consistent muscle gains as you go through your cycle of 12 weeks.
  • Huge strength stamina and endurance gains
  • No virilization
  • You will not have masculinization issues with LGD-3033 such as facial hair, back hair, or beards. So women are welcome to the club! (still, they need a doctor’s clearance before they decide to do LGD 3033)
  • Can lead to stronger bones
  • LGD 3033 can provide higher bone density.
  • Results from LGD 3033 can be surprisingly fast
  • Some users report seeing results in the first week although it is better to wait for the whole cycle to see those results
  • So far, LGD-3033 has shown very few side effects in comparison with other SARMS. Its benefits far outweigh its side effects (if any)

Side effects

LGD-3033 is relatively new, so it’s not surprising that you won’t get to know about most of its side effects for quite some time. A few side effects, however, have caught the eye of some keen users

Even with moderate dosages, the product can give you testosterone suppression, which means you will most likely need to do a PCT. 

Some people may experience increased libido. This is not universal, however, because interestingly others have an opposite effect, that is a reduction in libido.

Some men may experience men’s boobs or other estrogenic effects.

LGD-3033 tends to bind very strongly to androgenic receptors, thus crowding out testosterone from also attaching to those receptors.

We, therefore, end up with excess testosterone floating around with no receptors to attach to. This excess testosterone may convert to estrogen, causing excess estrogen levels, which in turn can lead to situations like men’s boobs.

To avoid this, you can use LGD-3033 with a daily dose of 25mg to 75 mg per day of Arimistane.  Arimistane helps to keep your estrogen levels low.


LGD-3033 can be taken orally both with food or not. However, the oral path is preferred.

 Fixing the dosage of a drug that’s still in development and is yet to be officially released for human use can be tricky. Such a task is usually left to the few brave souls in the user community willing to try it out for themselves by experimenting.

This SARMS has no official dosage, and so we have to work it out ourselves.

Its short half-life of just 6 hours means you need a higher frequency of it to have enough of it in our bodies to take you through the day.

So most users recommend 3 to 4 doses a day.  The amounts to take will depend on your bodybuilding goal (cutting, bulking or recomping)


Used for a cycle of 6 to 8 weeks, one can use between 15 mg and 20 mg each day.


To get the amazing results of dramatic muscle mass gain that LGD-3033 gives, it is recommended that you use between 20 mg and 30 mg each day going for an 8 to 10-week cycle.


Use the same dosage as bulking (15 mg to 20 mg each day) for a 6 to 8-week cycle.

Stacking Options

You can get even better results by stacking LGD-3033 with other SARMS. For example, you can stack it with LGD 4033 or with GW-501516.

Price and availability

LGD-3033 has not yet been released into the market. However, one can buy versions that purport to be LGD-3033 from the internet. To be honest, these are most likely fakes or other SARMS, so I advise those wanting to buy LGD-3033 to wait for the official release of the substance or use another SARMS such as LGD 4033.

How does LGD 3033 work?

This product, like other SARMS, works by binding onto androgenic receptors in the bone and muscle. We call it selective because unlike anabolic steroids which go for all androgenic receptors in the body, LGD-3033 is much more discriminating, targeting only bone or muscle receptors.

This makes LGD-3033 or SARMS much more preferable to anabolic steroids because they yield only the desired results while avoiding the bad effects of anabolic steroids. 

Note that SARMS can still cause some of the bad side effects of steroids but to a much-reduced extent. LGD-3033 is exceptional among the SARMS for its minimal side effects. This is because it has a much higher tissue selectivity while steering clear of the reproductive organs.


LGD-3033 might surprise everyone in due time as the best possible SARM yet. The available results from both the few published research and wide anecdotal evidence, suggests it is a very promising SARM combining that sweet spot of maximum benefits with minimum side effects.

Despite this optimism, I advise caution in using it because it is not yet fully studied, and it may have some undiscovered side effects.

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